Plant Transcription Factor Database
Previous version: v3.0
Nelumbo nucifera
ARF Family
Species TF ID Description
NNU_000459-RAARF family protein
NNU_001675-RAARF family protein
NNU_003220-RAARF family protein
NNU_003960-RAARF family protein
NNU_004968-RAARF family protein
NNU_005655-RAARF family protein
NNU_005712-RAARF family protein
NNU_009427-RAARF family protein
NNU_009693-RAARF family protein
NNU_010558-RAARF family protein
NNU_011379-RAARF family protein
NNU_012369-RAARF family protein
NNU_012419-RAARF family protein
NNU_013582-RAARF family protein
NNU_014217-RAARF family protein
NNU_016552-RAARF family protein
NNU_018202-RAARF family protein
NNU_018909-RAARF family protein
NNU_019598-RAARF family protein
NNU_020650-RAARF family protein
NNU_021433-RAARF family protein
NNU_021637-RAARF family protein
NNU_024648-RAARF family protein
NNU_025907-RAARF family protein
NNU_025919-RAARF family protein
ARF Family Introduction

Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.

Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.

The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.

Guilfoyle TJ, Hagen G.
Auxin response factors.
Curr Opin Plant Biol, 2007. 10(5): p. 453-60.
PMID: 17900969